HuntsvilleRecruiter Since 2001
the smart solution for Huntsville jobs

Associate Director Biochemistry and Biophysics

Company: American Society for Biochemistry and Molecular Bi
Location: Lexington
Posted on: February 23, 2021

Job Description:

American Society for Biochemistry and Molecular Biology

  • Associate Director Biochemistry and Biophysics Associate Director Biochemistry and Biophysics Associate Director, Biochemistry and Biophysics The ideal candidate will provide experienced leadership in overseeing the development and implementation of biochemical and biophysical assays for hit screening and lead optimization and will collaborate cross-functionally to support drug discovery efforts across the portfolio. This individual will be an expert in enzymology and have a broad understanding of current assay technologies, instrumentation, and screening formats required to identify and characterize small molecule inhibitors of enzymes and protein-protein interactions. Candidates experienced in DNA damage response biology and with experience successfully managing external service providers will be prioritized. Job Responsibilities:
    • Lead a team of scientists in the design, development, validation, and implementation of a broad range of biochemical assays for small molecule screens against novel targets in DNA damage response pathways
    • Establish and manage collaborations with external CROs performing assay development and miniaturization, assay transfer, library screening, hit validation, and biophysical characterization of lead compounds across projects
    • Oversee protein production and purification to support biochemical and biophysical assay development
    • Develop expert knowledge of biochemical mechanisms of program targets and DDR biology and serve on cross-functional project teams as the biochemistry expert
    • Lead productive discussions on key scientific and strategic issues with internal and external colleagues at all levels of the organization
    • Stay current with new technologies and relevant scientific advances in biochemical techniques and assay formats from literature, scientific meetings, and professional network
    • Review and ensure the quality of scientific data to meet regulatory expectations and author technical and regulatory documents to support advancement of therapeutics to clinical testing
    • Act in accordance with all Cyteir Therapeutics policies and be a positive contributor to company culture Requirements Job Qualifications:
      • PhD and 8+ combined years of postdoctoral research experience and/or industry experience developing and implementing biochemical and biophysical assays to support drug discovery
      • Expertise in the areas of enzymology, enzyme kinetics and current assay formats for several enzyme classes and protein-protein-interaction targets and experience with high-throughput screening and hit validation
      • Hands-on experience performing biophysical techniques such as SPR, ITC, and DSF
      • Experience with mass spectrometry, proteomics, and protein crystallography will be prioritized
      • General knowledge of early drug discovery process and demonstrated leadership on cross-functional teams
      • Demonstrated success using in-house and external resources to advance programs from assay development to drug candidate characterization
      • Well organized and able to maintain detailed records of experimental work
      • Ability to communicate clearly and decisively in an open, timely manner
      • Demonstrated ability to effectively train, manage, and mentor junior scientists
      • A sense of adventure and excitement to help build a successful biotech company and work in a highly dynamic research environment Job Information
        • Job ID: 55875856
        • Location:
          Lexington, Massachusetts, United States
        • Position Title: Associate Director Biochemistry and Biophysics Precision targeting of key DNA repair mechanisms is the key to synthetic lethal therapies for cancer and autoimmune disease. In contrast to other therapies which completely eliminate the target's activity (e.g. kinase inhibitors), the key to targeting DNA repair is to partially reduce or precisely alter the activity of specific DNA repair factors. In this way, target cells with genetically defined gain-of-function abnormalities will self-destruct without harming healthy tissues. This works because cells with certain gain-of... Research Associate Translational Research Lexington, Massachusetts, United States 3 days ago Senior/Principal Scientist - Discovery Biology Senior Research Associate, Biochemistry &... LifeMine Therapeutics Cambridge, Massachusetts, United States QU Quinnipiac University QU Quinnipiac University EM Scientist II, AAV External Analytical Development... 11200 Rockville Pike, Suite 302Rockville, Maryland 20852(240) 283-6590

Keywords: American Society for Biochemistry and Molecular Bi, Huntsville , Associate Director Biochemistry and Biophysics, Executive , Lexington, Alabama

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category

Other Executive Jobs

Strategic Programs Manager
Description: Company Overview:At ADT, we've been in the business of helping save lives for more than 145 years. As the number one smart home security provider serving residential and business customers, our people (more...)
Company: ADT
Location: Birmingham
Posted on: 03/3/2021

Operations Manager - Birmingham, AL
Description: Company Overview:At Veo, we're bringing the next generation of mobility sharing to cities and universities globally through our dockless pedal bike, e-bike and e-scooter systems. We also offer fat-tire (more...)
Company: Veo
Location: Birmingham
Posted on: 03/3/2021

Description: Job Description - ASSOCIATE DIRECTOR ADMISSIONS T184490 ASSOCIATE DIRECTOR ADMISSIONS - T184490 This position is responsible for recruiting
Company: CTI Education Group
Location: Birmingham
Posted on: 03/3/2021

Restaurant Manager
Description: Overview: When working at Cracker Barrel, you will enjoy a fast-paced, family environment, where we treat every guest as a guest in our own home. You ll be Pleasing People with our made-from-scratch recipes (more...)
Company: Cracker Barrel
Location: Calera
Posted on: 03/3/2021

Restaurant Manager
Description: Overview: When working at Cracker Barrel, you will enjoy a fast-paced, family environment, where we treat every guest as a guest in our own home. You ll be Pleasing People with our made-from-scratch recipes (more...)
Company: Cracker Barrel
Location: Oxford
Posted on: 03/3/2021

Territory Manager, Acute Pain
Description: Title:--Territory Manager, Acute PainRegion:--Birmingham, AL Ideal Candidate Location: Field Based/Remote near Birmingham, AL Purpose of the Position:Reporting to the Regional Business Leader, the Territory (more...)
Company: Avanos Medical
Location: Birmingham
Posted on: 03/3/2021

Regional Medical Director (Alabama
Description: Overview br br The Medical Director is responsible for setting the highest standard of care and working with doctor teams to achieve that standard. Regional Medical Directors team with Regional Operations (more...)
Company: Southern Veterinary Partners
Location: Birmingham
Posted on: 03/3/2021

Store Manager
Description: OverviewAs a Store Manager SM , you will serve as second-in-command to a team dedicated to making a difference. Whether it's building customer relationships or demonstrating new sales techniques, you (more...)
Company: TMX Finance Family of Companies
Location: Birmingham
Posted on: 03/3/2021

Engineering Manager/Principal Systems Engineer (Electronics - Defense - Aviation - Aeronautics)
Description: Engineering Manager/Staff Systems EngineerTalladega, AL areaOverview:USPRO is looking for a proven Engineering resource--to work with a defense client of ours in the Talladega, Alabama area. This individual (more...)
Company: USPRO
Location: Talladega
Posted on: 03/3/2021

NIS - Security Assurance Director
Description: You with industry visionaries with new possibilities Job Category Information Security Line of Service Internal Firm Services Level Director Specialty/Competency IFS - Information Technology IT Industry/Sector (more...)
Location: Birmingham
Posted on: 03/3/2021

Log In or Create An Account

Get the latest Alabama jobs by following @recnetAL on Twitter!

Huntsville RSS job feeds